Trace Label Fluorescence Scanner

Identify more leads for greater crystallization success!!

Why protein crystallographers use trace label fluorescence imaging:

• Stunning signal-to-noise ratio yields significantly higher crystallization identification hit rate.

• Remove the uncertainty caused by large variations in signal intensity observed when using intrinsic tryptophan-based fluorescence.

• Simple, fast and flexible labelling kit (MD1-65) 0.02% label has no proven effect on the protein, crystallization or data quality. View simple protocol here.

• Label two components with different colour dyes - uniquely check both parts of a complex are in the crystal.

• No false positives or negatives unlike other salt/protein differentiation techniques.

• Harmless LEDs - no risk of damage to you or the crystals (see diffraction image below).

Watch the video of Simple, Definitive and Safe protein crystal identification today..............

Overview of Crystal X2 (MD5-700):

• Provides fully automated white light and/or multiple fluorescence images.

• Compatible with all SBS crystallization plates - single plate system.

• Operating range of 4-30 °C.

• Long lifetime LEDs (50,000 hours).

• Simple easy-to-use software included.

Diffraction image of of labelled protein shows no effect on the crystal.

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Trace Fluorescent Labelling kit (Single colour) MD1-73	Datasheet : Download
A 10 experiment kit for Trace Fluorescent labelling of proteins. This kit contains only the Carboxyrhodamine (green dye). Read more..

Trace Fluorescent Labelling kit - Dual (2 colour) MD1-72	Datasheet : Download
A 10 experiment kit for Trace Fluorescent labelling of proteins. This kit contains both the Carboxyrhodamine (green dye) and also Texas Red (red dye) for labelling two components of a Protein complex. Read more..

Crystal X2
MD5-700

NEW..............

CrystalX2 is an automated LED based plate scanner designed to utilize non-hazardous green light wavelengths in protein crystal identification. The system uses trace Label (TL) Fluorescence - the addition of tiny amounts (<0.02% label) of a covalent fluorescent dye to the protein prior to crystallization in order to rapidly identify even the smallest protein crystals.

SIGN UP NOW for the WEBINAR - to be held on Tuesday the 30th April at 08:00 PDT, 11:00 EDT, 16:00 GMT and 17:00 CET.
Title: "Trace Labeling Technique Finds Crystal Leads Sooner - See the CrystalX2 Automated Lead Finder in a LIVE Demonstration".

An example of the output from the CrystalX2:

See how easy it is to identify crystallization leads (the bright green spots):

Watch the CrystalX2 video now..............

Download CrystalX2 Datasheet

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"We much prefer screens from the Molecular Dimesions because of greater consistency between the batches, very clear blue/yellow labelling and absolutely great customer service!" University of Cambridge, UK

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