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Rest of the World

Tel.: +44 1638 561051
Fax: +44 1638 660674

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Park, Willie Snaith Road
Newmarket
Suffolk CB8 7SQ

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USA, Canada,
and South America

Tel. +1 877 479 4339
Fax: +1 321 972 8896

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Florida, 32714

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In partnership with
Oxford Cryosystems
for North America, Canada
and South America

 

Introducing CryoSol™ – Worry free ligand solubilization and
crystal cryocooling
Dilvac Dewar Flasks with replaceable glass
WIN!! - Beats Headphones, Just send us your Crystal Photographs


CryoSol™ - Solubilize hydrophobic ligands for co-crystallization
and cryoprotection

Developed in the Laboratory of Dr. Enrico Stura at CEA Saclay, France CryoSol™ is an extended set of multicomponent solutions intended for crystal cryoprotection and soaking of hydrophobic ligands into crystals.

a) Crystals of TTR grown in complex with curcumin
b) Crystal structure of TTR-curcumin complex following further soaking in a cryosol solution with curcumin (PDB: 4PMF).

  • Simultaneously soak in your molecule and cryoprotect your crystal
  • Co-crystallize with hydrophobic compounds (ligands, inhibitors, cofactors, coenzymes etc.)
  • Designed to improve diffraction resolution and reduce mosaicity

References
Ciccone L., Vera L., Tepshi L., Rosalia L., Rossello A. & Stura E.A.(2015) Multicomponent mixtures for cryoprotection and ligand solubilization. (ICCBM15 poster) Biotechnol. Reports (submitted)

Ciccone L, Tepshi L, Nencetti S, Stura EA.N Biotechnol. (2015) “Transthyretin complexes with curcumin and bromo-estradiol: Evaluation of solubilizing multicomponent mixtures” 32(1):54-64.
L Vera, EA Stura - Crystal Growth & Design, (2014) “Strategies for Protein Cryocrystallography”14 (2), 427-435..


Dilvac Dewar Flasks

Check out our new range of Dilvac Dewar flasks. Manufactured to exacting standards and represent the highest quality dewars available today for laboratory use.

  • For cryocooling crystals, biological samples and working with cryotools etc.
  • High-quality stainless steel containers - rust-free, anti-corrosive, hygienic and strong
  • Replaceable glass

 


Win a set of Beats™ by Dr. Dre
in our Crystal Photograph Competition

Throughout 2015 we will be running a quarterly competition
to win a prize for the best image of a crystal grown in our screens.

Simply email your picture to us to have a chance
to win the winner will be announced on Thursday 2nd April.


Photos submitted will be displayed on our social media pages.

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and Facebook



Don't forget we can help make your life easier and save you money with our Custom made Optimization and Crystallization Screen service.


I am looking for........

Accelerate crystallization.... Naomi's Nucleant
Optimise a membrane protein lead.... Additive kits
Datasheets and articles for our screens..... Datasheets & Literature



See what else is new at Molecular Dimensions

 

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