3D Structure Screen MD1-13

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Determine the role of precipitant concentration using the 3D Structure Screen.

The 3D Structure Screen is formulated for growing protein crystals in the metastable zone using the vapour diffusion technique. This method is presented in the 3D Structure Screen as a sparse matrix crystal growth screen which allows 24 "nucleation” conditions and 24 "backed-off” conditions for crystal growth to be tried.

  • Separate nucleation from crystal growth.
  • A simple method for growing crystals in the metastable zone.
  • Obtain much larger and better diffracting crystals compared to conventional methods.

A 48 x 10 mL sparse matrix screen.

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