MemStart™ MD1-21

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A starting point for screening and optimizing crystallization conditions for alpha - helical type transmembrane proteins using vapour diffusion methods.

A targeted sparse matrix of 48 conditions (10 ml) allowing the pH range, precipitants and salts used in membrane protein crystallization to be screened with detergent- containing protein drop.

  • Based on the reagents typically used in the laboratory of Prof. S. Iwata, Imperial College, UK.
  • Optimized to span 33 reported successful crystallization conditions for which high resolution structures of membrane proteins have been determined, including pH, type of precipitant, precipitant concentration, and salts.

  • Keywords: membrane protein crystallography, membrane protein crystals, membrane protein screen, Iwata group, MbClass, MembFac.

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