MemChannel™ MD1-110 / 111 / 111-FX
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The first crystallization screen developed specifically for ion channel proteins:
- MemChannel™* uniquely targets ion channel proteins.
- Includes the most common ion channel crystallization conditions to maximize your chances of success.
- Continually updated database3 ensures most recent hit conditions are present.
- Hand-curated to remove false positives from unrelated structures – only ion channel crystallizations contribute to the formulation.
- Developed by Prof. Simon Newstead and Dr Joanna Parker who developed our popular MemGold™ screens.
- Exclusively available from Molecular Dimensions.
Since releasing the popular MemGold and MemGold II1,2 screens, Prof. Simon Newstead of Oxford University has continued to hand-curate his database3 of α-helical membrane protein structures and their crystallization conditions.
The database3 is now large enough to allow robust analysis of functional sub-groups within the dataset as a whole. This has resulted in the development of a new-generation of screens, including MemChannel, focused on particular classes of membrane protein.
References
- Newstead, S., Ferrandon, S., Iwata, S. Protein Science 17: 466-472 (2008).
- Parker, J. and Newstead, S. Protein Science 21: 1358-1365 (2012).
- Parker, J. L. and Newstead, S. Adv. Exp. Med. Biol. 922: 61-72 (2016).
*Developed by Prof. Simon Newstead and Dr Joanne Parker of Oxford
University and exclusively licensed to Molecular Dimensions Ltd by
Oxford University Innovation.
