The Morpheus® Additive Screen MD1-93

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The Morpheus® Additive Screen is a new 96-condition additive screen, containing an extensive library of ligands suitable for soluble and membrane proteins.

Features of The Morpheus® Additive Screen:

  • Contains all the compounds from the successful Morpheus® and Morpheus® II screens
  • Test a large range of precipitants, stabilizers, buffers, nucleants, phasing compounds, cryoprotectants and surfactants all in one screen.
  • Enhance stability and solubility of protein for crystallization with the inclusion of NDSBs, polyamines, monosaccharides and amino acids.
  • Contains heavy atoms as additives for experimental phasing.
  • Use in protein stability screen assays e.g. thermal shift assays.
  • Suitable for both soluble and membrane proteins.

MD1-93 is presented as 96 x 100 µL conditions in a foil sealed plate.

References
  1. Gorrec, F (2009), The MORPHEUS protein crystallization screen J Appl Cryst, 42, 1035-1042.
  2. Gorrec, F (2013), The current approach to initial crystallization screening of proteins is under-sampled J Appl Cryst , 46, 795-797.
  3. Gorrec, F (2015), The Morpheus II protein crystallization screen, ICCBM15 proceedings Acta Cryst F71, p. 831-837.

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