A starting point for screening and optimizing crystallization conditions for alpha type transmembrane proteins using vapour diffusion methods.
A sparse matrix of 48 conditions allowing the pH range, precipitants and salts used in membrane protein crystallization to be screened with detergent- containing protein drops.
Molecular Dimensions acknowledges the work of Prof. S. Iwata, Dr. M. Iwata and Dr. J. Abramson in designing this product.
Features of MemStart™:
- Based on the reagents typically used in the laboratory of Prof. S. Iwata.
- Optimized to span 33 reported successful crystallization conditions of membrane proteins for which atomic resolution structures have been determined.
- Includes the pH, precipitant concentration and type, and salts found to be successful.
This product is manufactured under an exclusive license from Imperial College of Science, Technology & Medicine, London, UK.
Methods and Results in the crystallization of Membrane proteins (2003) Ed. Iwata S. (International University Line)
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